Patient Resources

Our Message to You

At Cellectar, we are committed to responsibly advancing our investigational therapies for patients with limited treatment options. Many of us have personally witnessed the impact of cancer on our families and communities, which fuels our dedication to developing potential new treatments that may improve patient outcomes.

We conduct our research with integrity and scientific rigor, prioritizing patient safety and quality of life throughout every stage of development.

To learn more about our ongoing clinical studies, including our pediatric high-grade glioma study for adolescents and young adults, please visit our Clinical Studies page, or or visit www.pediatrictrials.org.

Clinical Studies Overview

Clinical studies play a vital role in the discovery and development of new cancer therapies. Participation in these studies helps researchers gather valuable information that may advance future treatment options.

For general information about clinical trials, visit www.cancer.org or explore our Clinical Studies section.

Disease Education and Resources

We believe informed patients and caregivers are better equipped to make shared treatment decisions. Cellectar provides educational information about the cancers studied in our clinical research programs to help patients and families access credible, up-to-date resources.

For additional information and support, please visit www.cancer.org.

What is Waldenström Macroglobulinemia?¹

Waldenström macroglobulinemia (WM) is a rare, slow-growing cancer of the lymphatic system. Cancers of the lymphatic system are called lymphomas. WM is a type of lymphoma called non-Hodgkin lymphoma. Non-Hodgkin lymphoma is not a single disease; it refers to a group of different lymphomas that start in the lymphocytes (white blood cells). WM affects a specific type of white blood cell, called a b-lymphocyte, or b-cell for short. Additional Resources for patients and caregivers affected by Waldenström macroglobulinemia:

International Waldenstrom’s Macroglobulinemia Foundation LymphomaHub

¹International Waldenstrom’s Macroglobulinemia Foundation - https://iwmf.com/what-is-wm-lpl.

Pediatric and Adolescent Cancers

Several types of cancers are being evaluated in this clinical study. They are:

High-Grade Glioma

A high-grade glioma is a type of tumor formed in the brain or spinal cord (central nervous system, or CNS) through the abnormal growth of glial cells. Glial cells surround, protect, and help with the functions of neurons — the cells that help send messages from your brain to the rest of your body. Gliomas are classified into different tumor types based on which glial cells the tumor developed from, what part of the brain the tumor grows in, and how aggressive the tumor cells appear under the microscope. There are four different types of glial cells that can turn into a glial tumor: ependymal cells, microglia, astrocytes, and oligodendrocytes. Then gliomas are also categorized into four different grades, based on how aggressive the tumor cells are and how fast the tumor grows. High-grade gliomas are graded as a 3 or 4, indicating they are more aggressive and grow more rapidly.

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Ependymoma

Ependymoma is the growth of cells that form in the brain or spinal cord. The cells form a mass called a tumor. Ependymoma begins in the ependymal cells. These cells line the passageways that carry cerebrospinal fluid. This fluid surrounds and protects the brain and spinal cord.

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Diffuse Intrinsic Pontine Glioma

Diffuse intrinsic pontine glioma is a type of brain tumor found in an area of the brainstem known as the pons. The name diffuse intrinsic pontine glioma describes how the tumor grows, where it is found, and what kinds of cells give rise to the tumor.

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