Cellectar Biosciences, Inc.

Advancing Innovation in Targeted Therapies

Drug conjugate approaches have faced many challenges, including limited to no improvement in toxicities and clinical efficacy. These issues can often be traced back to the mechanism used to target the tumor cells. Understanding this challenge, Cellectar has taken a novel approach to pursue a means of targeting cancers in a manner that takes advantage of the increased metabolic needs of all cancers and allows our compounds to gain entry directly into the tumor cell’s cytoplasm. In order to satisfy its increased metabolism, tumor cells change regions on the cell surface; these changes in the cell surface are what our PLEs target. These changes are unique to tumor cells and do not occur in highly metabolic normal cells. Importantly, because nearly all tumor cells and all tumor types have increased metabolic needs, our molecules can target the primary tumor, any metastatic tissue and the cancer stem cells regardless of the tumor type or location.