Creating the Next Generation of Targeted Cancer Therapies

We are a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer. We are developing proprietary drugs independently and through research and development collaborations with a core objective to leverage its proprietary Phospholipid Drug Conjugate™ (PDC) delivery platform to develop PDCs that specifically target cancer cells, delivering improved efficacy and better safety as a result of fewer off-target effects. Our PDC platform possesses the potential for the discovery and development of the next-generation of cancer-targeting treatments, and we plan to develop PDCs independently and through research and development collaborations.

A Multi-Asset Product Portfolio of Chemotherapeutics

We employ a drug discovery and development approach that allows us to efficiently design and develop drug candidates rapidly. In just a couple of years, we have successfully advanced our lead PDC, iopofosine into multiple clinical studies in many cancers including a pivotal study for Waldenstrom’s macroglobulinemia. Additionally, we have rapidly progressing proprietary preclinical programs utilizing different payloads and have established several strategic collaborations.

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Advancing Innovation in Targeted Therapies

Drug conjugate approaches have faced many challenges, including limited to no improvement in toxicities and clinical efficacy. These issues can often be traced back to the mechanism used to target the tumor cells. Understanding this challenge, Cellectar has taken a novel approach to pursue a means of targeting cancers in a manner that takes advantage of the increased metabolic needs of all cancers and allows our compounds to gain entry directly into the tumor cell’s cytoplasm. In order to satisfy its increased metabolism, tumor cells change regions on the cell surface; these changes in the cell surface are what our PLEs target. These changes are unique to tumor cells and do not occur in highly metabolic normal cells. Importantly, because nearly all tumor cells and all tumor types have increased metabolic needs, our molecules can target the primary tumor, any metastatic tissue and the cancer stem cells regardless of the tumor type or location.

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Corporate Presentation - April 2024
July 14, 2024
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"A commitment to the personal growth and professional development of our employees is the foundation of our high-performance company."

– Jim Caruso
President and CEO

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Cellectar Biosciences, Inc.
100 Campus Drive, Suite 207
Florham Park, NJ 07932
T: 608-441-8120

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