Form: EFFECT

Notice of Effectiveness

February 7, 2011

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Notice of Effectiveness
Effectiveness Date: February 7, 2011
Accession Number: 0001144204-11-006033
Submission Type: POS AM
CIK: 0001279704
Company Name: NOVELOS THERAPEUTICS, INC.
File Number: 333-161922