424B3: Prospectus filed pursuant to Rule 424(b)(3)
Published on July 20, 2007
Filed
pursuant to Rule 424(b)(3)
File
Nos. 333-133043
333-129744
Prospectus
Supplement No. 3
(To
Prospectus dated March 28, 2007)
NOVELOS
THERAPEUTICS, INC.
34,285,449
shares of common stock
This
prospectus supplement supplements the Prospectus dated March 28, 2007, relating
to the resale of 34,285,449 shares of our common stock. This prospectus
supplement should be read in conjunction with the Prospectus.
Amendment
to Amended and Restated Certificate of Incorporation
On
July
16, 2007, our shareholders approved an amendment to our Amended and Restated
Certificate of Incorporation to increase to 150,000,000 the number of shares
of
common stock, par value $.00001, we are authorized to issue (the “Amendment”).
The Amendment became effective on July 16, 2007 upon the filing of the Amendment
with the Delaware Secretary of State’s office.
Investing
in our common stock involves a high degree of risk.
See
Risk Factors beginning on page 7 of the Prospectus.
Neither
the Securities and Exchange Commission nor any state securities commission
has
approved or disapproved of these securities or passed on the adequacy or
accuracy of this prospectus supplement. Any representation to the contrary
is a
criminal offense.
The
date
of this prospectus supplement is July 20, 2007